node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCP_2438 | glyA | MCP_2438 | MCP_0294 | Asparagine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
MCP_2438 | purD | MCP_2438 | MCP_2597 | Asparagine synthase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.937 |
MCP_2438 | purE | MCP_2438 | MCP_0125 | Asparagine synthase. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.889 |
MCP_2438 | purL | MCP_2438 | MCP_1797 | Asparagine synthase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.963 |
MCP_2438 | purM | MCP_2438 | MCP_2729 | Asparagine synthase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.937 |
MCP_2438 | purQ | MCP_2438 | MCP_1798 | Asparagine synthase. | Phosphoribosylformylglycinamidine synthase I. | 0.941 |
MCP_2438 | purT-1 | MCP_2438 | MCP_2477 | Asparagine synthase. | Phosphoribosylglycinamide formyltransferase 2. | 0.805 |
MCP_2438 | purT-2 | MCP_2438 | MCP_2878 | Asparagine synthase. | Phosphoribosylglycinamide formyltransferase 2. | 0.805 |
MCP_2478 | MCP_2479 | MCP_2478 | MCP_2479 | Putative DNA mismatch repair protein. | Putative DNA mismatch repair protein. | 0.842 |
MCP_2478 | purT-1 | MCP_2478 | MCP_2477 | Putative DNA mismatch repair protein. | Phosphoribosylglycinamide formyltransferase 2. | 0.736 |
MCP_2479 | MCP_2478 | MCP_2479 | MCP_2478 | Putative DNA mismatch repair protein. | Putative DNA mismatch repair protein. | 0.842 |
MCP_2479 | purT-1 | MCP_2479 | MCP_2477 | Putative DNA mismatch repair protein. | Phosphoribosylglycinamide formyltransferase 2. | 0.736 |
glyA | MCP_2438 | MCP_0294 | MCP_2438 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Asparagine synthase. | 0.928 |
glyA | purD | MCP_0294 | MCP_2597 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.898 |
glyA | purE | MCP_0294 | MCP_0125 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.471 |
glyA | purL | MCP_0294 | MCP_1797 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.865 |
glyA | purM | MCP_0294 | MCP_2729 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.780 |
glyA | purQ | MCP_0294 | MCP_1798 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylformylglycinamidine synthase I. | 0.668 |
glyA | purT-1 | MCP_0294 | MCP_2477 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylglycinamide formyltransferase 2. | 0.918 |
glyA | purT-2 | MCP_0294 | MCP_2878 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylglycinamide formyltransferase 2. | 0.918 |