Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trkA-2Trk system potassium uptake protein TrkA homolog. (216 aa)    
Predicted Functional Partners:
MCP_2505
Trk system potassium uptake protein.
 
 
 0.982
MCP_0548
Trk system potassium uptake protein.
 
 
 0.937
MCP_1060
Conserved hypothetical protein; Belongs to the UPF0288 family.
   
    0.739
MCP_2421
Molybdopterin-guanine dinucleotide biosynthesis MobB/molybdopterin biosynthesis MoaE; Bifunctional protein.
  
    0.692
hemD
uroporphyrinogen-III synthase.
  
    0.675
MCP_0857
Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
   
    0.653
MCP_2507
Hypothetical protein.
       0.554
MCP_1491
Amino acid transporter.
  
  
 0.534
MCP_1966
Amino acid transporter; Contains two UspA domains (IPR006016).
  
  
 0.526
aroA-2
Putative aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
  
  
 0.435
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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