STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cbiX-2Sirohydrochlorin cobaltochelatase. (118 aa)    
Predicted Functional Partners:
thiC
Thiamine biosynthesis protein ThiC.
     
 0.801
cobA
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.603
cysG
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Bifunctional protein.
  
  
 0.594
MCP_2530
Conserved hypothetical protein; Contains one Beta-lactamase-like domain (IPR001279).
     
 0.566
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 0.518
MCP_0919
Conserved hypothetical protein.
  
     0.467
MCP_2219
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF171 family (IPR003750).
  
     0.451
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
      
 0.449
MCP_0363
Conserved hypothetical protein.
 
   
 0.428
MCP_1358
Putative phosphoadenosine phosphosulfate reductase.
  
  
 0.425
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.