Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_2552TraB family protein. (415 aa)    
Predicted Functional Partners:
MCP_2553
Peptidase M50 family protein; Belongs to the peptidase M50B family.
       0.783
dnaJ
Heat shock protein 40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...]
  
 
   0.643
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
   0.599
MCP_0233
Similar to peptide synthetase AdpD in Anabaena circinalis 90 (Q9K5L9).
   
   0.598
MCP_2009
Conserved hypothetical protein; Contains one Heat shock protein DnaJ, N-terminal domain (IPR001623).
    
   0.596
echF
Ech hydrogenase subunit F.
    
   0.593
MCP_0487
Conserved hypothetical protein; Contains at least two Regulator of chromosome condensation, RCC1 repeats (IPR000408).
    
   0.593
MCP_1625
Hypothetical protein; Contains four Regulator of chromosome condensation, RCC1 repeats (IPR000408).
    
   0.593
MCP_2638
4Fe-4S ferredoxin, iron-sulfur binding protein.
    
   0.593
MCP_0232
Putative acyl-CoA synthetase.
   
   0.583
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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