STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2556Conserved hypothetical protein; Belongs to the tRNAHis guanylyltransferase family (IPR007537). (247 aa)    
Predicted Functional Partners:
MCP_2554
Conserved hypothetical protein; Contains one PRC-barrel domain (IPR007903).
       0.582
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
    
 
 0.563
MCP_2555
MFS transporter; Similar to Multidrug resistance protein mdtH in Escherichia coli (P69367).
       0.554
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
 
   
 0.532
nadX
Probable L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
       0.529
MCP_1751
Conserved hypothetical protein; Similar to JAMM-like protein in Archaeoglobus fulgidus (O28085, AF_2198).
  
    0.526
MCP_0555
Conserved hypothetical protein; Contains one TfuA-like, core domain (IPR012924).
  
     0.489
MCP_2322
Conserved hypothetical protein; Contains one RNA binding S1 domain (IPR003029); Contains one RNucleic acid binding, OB-fold, tRNA/helicase-type domain (IPR004365).; Contains one Phosphoesterase, RecJ-like (IPR001667).
  
     0.438
mtrH
Tetrahydromethanopterin S-methyltransferase subunit H.
  
     0.414
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: medium (48%) [HD]