Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hypBPutative hydrogenase nickel incorporation protein HypB. (216 aa)    
Predicted Functional Partners:
hypA
Probable hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.993
hypD
Hydrogenase expression/formation protein HypD.
 
  
 0.989
hypF
Carbamoyltransferase HypF.
 
   
 0.951
hypC
Hydrogenase expression/formation protein HypC.
 
  
 0.933
hypE
Hydrogenase expression/formation protein HypE.
 
  
 0.872
MCP_2640
Putative [NiFe]-hydrogenase large subunit.
   
 
 0.852
vhtG
F420-non-reducing hydrogenase small subunit.
 
  
 0.759
echE
Ech hydrogenase subunit E.
   
 
 0.698
MCP_0523
[NiFe]-hydrogenase large subunit; Similar to Ech hydrogenase, subunit EchE in Methanosarcina barkeri (O59656).
   
 
 0.698
frhA-1
Coenzyme F420 hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.649
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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