Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2586Conserved hypothetical protein; Contains one Bacterio-opsin activator, HTHdomain (IPR007050). (207 aa)    
Predicted Functional Partners:
rocF
Arginase; Belongs to the arginase family.
       0.658
MCP_2734
Conserved hypothetical protein.
  
     0.613
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.553
MCP_1816
Conserved hypothetical protein; Involved in DNA damage repair.
 
     0.519
MCP_1249
Conserved hypothetical protein.
  
     0.512
MCP_2737
Conserved hypothetical protein.
  
     0.456
MCP_1884
Putative phosphate transport system protein.
  
     0.419
MCP_0536
Putative histidine kinase; Contains one ATP-binding region, ATPase-like domain (IPR003594).
  
     0.415
MCP_0329
Putative transcriptional regulator.
  
     0.411
MCP_0053
Hypothetical protein.
  
     0.400
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.