Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hypCHydrogenase expression/formation protein HypC. (81 aa)    
Predicted Functional Partners:
hypE
Hydrogenase expression/formation protein HypE.
 
 
 0.993
hypD
Hydrogenase expression/formation protein HypD.
 
 
 0.988
hypA
Probable hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.956
hypB
Putative hydrogenase nickel incorporation protein HypB.
 
  
 0.933
hypF
Carbamoyltransferase HypF.
 
 
 0.880
vhtG
F420-non-reducing hydrogenase small subunit.
  
 
 0.683
MCP_2640
Putative [NiFe]-hydrogenase large subunit.
   
 
 0.640
vhtA
F420-non-reducing hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.636
vhtD
Putative F420-nonreducing hydrogenase subunit D.
  
  
 0.540
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.529
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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