STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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MCP_26602-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (300 aa)    
Predicted Functional Partners:
MCP_2676
Conserved hypothetical protein; Belongs to the GHMP kinase-like, archaeal family (IPR012043).
    
 0.947
thiI
Probable thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.711
hflX
GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.689
MCP_2658
Conserved hypothetical protein.
       0.686
MCP_2267
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF137 family (IPR002855).
 
   
 0.594
MCP_0508
Similar to L(+)-tartrate dehydratase subunit beta TtdB in Escherichia coli. (P0AC35).
  
    0.557
MCP_0730
Putative RNA methyltransferase.
       0.536
ogt
methylated-DNA--protein-cysteine methyltransferase.
       0.536
MCP_0509
Similar to L(+)-tartrate dehydratase subunit alpha TtdB in Escherichia coli. (P05847).
       0.529
dfp
Bifunctional protein.
  
  
 0.499
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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