STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2661Archaeal histone. (70 aa)    
Predicted Functional Partners:
MCP_2990
Single-stranded DNA-binding replication protein.
 
  
 0.671
tfe
Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...]
  
   
 0.667
thrS
threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.637
MCP_0574
Conserved hypothetical protein; Contains one PilT protein, N-terminal domain (IPR002716); Contains one Nucleotide binding protein, PINc domain (IPR006596).; Contains one Bacterial type II secretion system protein E domain (IPR001482).; Contains one KH, type 1 domain (IPR004088).
 
     0.586
MCP_0190
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF63 family (IPR002749).
 
     0.583
MCP_0251
Truncated threonyl-tRNA synthetase.
  
    0.572
rnp3
Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.549
MCP_2662
Hypothetical protein.
       0.522
MCP_2570
Conserved hypothetical protein; Belongs to the Bacterial type II secretion system protein family (IPR001992).
  
     0.518
recJ
Single-stranded DNA-specific exonuclease RecJ.
  
     0.509
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.