| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCP_0351 | MCP_2857 | MCP_0351 | MCP_2857 | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | Archaeosine tRNA-ribosyltransferase. | 0.408 |
| MCP_0351 | dnaG | MCP_0351 | MCP_0113 | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.457 |
| MCP_0351 | eif2b | MCP_0351 | MCP_0370 | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | Translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.670 |
| MCP_0351 | pfdB | MCP_0351 | MCP_2622 | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.429 |
| MCP_0351 | priA | MCP_0351 | MCP_1539 | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...] | 0.416 |
| MCP_0351 | ribK | MCP_0351 | MCP_2669 | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.677 |
| MCP_0742 | ribK | MCP_0742 | MCP_2669 | Putative translin. | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.693 |
| MCP_0742 | ribL | MCP_0742 | MCP_1752 | Putative translin. | Putative cytidyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.449 |
| MCP_2857 | MCP_0351 | MCP_2857 | MCP_0351 | Archaeosine tRNA-ribosyltransferase. | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | 0.408 |
| MCP_2857 | dnaG | MCP_2857 | MCP_0113 | Archaeosine tRNA-ribosyltransferase. | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.550 |
| MCP_2857 | pfdB | MCP_2857 | MCP_2622 | Archaeosine tRNA-ribosyltransferase. | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.660 |
| MCP_2857 | priA | MCP_2857 | MCP_1539 | Archaeosine tRNA-ribosyltransferase. | Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...] | 0.558 |
| MCP_2857 | ribK | MCP_2857 | MCP_2669 | Archaeosine tRNA-ribosyltransferase. | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.681 |
| dnaG | MCP_0351 | MCP_0113 | MCP_0351 | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | 0.457 |
| dnaG | MCP_2857 | MCP_0113 | MCP_2857 | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Archaeosine tRNA-ribosyltransferase. | 0.550 |
| dnaG | eif2b | MCP_0113 | MCP_0370 | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.555 |
| dnaG | pfdB | MCP_0113 | MCP_2622 | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.670 |
| dnaG | priA | MCP_0113 | MCP_1539 | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...] | 0.887 |
| dnaG | ribK | MCP_0113 | MCP_2669 | Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.761 |
| eif2b | MCP_0351 | MCP_0370 | MCP_0351 | Translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | Conserved hypothetical protein; Contains one Nucleotide binding protein, PINc domain (IPR006596). | 0.670 |
