node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCP_1048 | MCP_1651 | MCP_1048 | MCP_1651 | 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine reductase. | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | 0.912 |
MCP_1048 | ribB | MCP_1048 | MCP_2670 | 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine reductase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.882 |
MCP_1048 | ribH | MCP_1048 | MCP_1453 | 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine reductase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.896 |
MCP_1651 | MCP_1048 | MCP_1651 | MCP_1048 | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine reductase. | 0.912 |
MCP_1651 | dfp | MCP_1651 | MCP_2675 | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | Bifunctional protein. | 0.406 |
MCP_1651 | ribB | MCP_1651 | MCP_2670 | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.880 |
MCP_1651 | ribH | MCP_1651 | MCP_1453 | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.869 |
MCP_2668 | ribB | MCP_2668 | MCP_2670 | Putative Na(+)/H(+) antiporter. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.553 |
MCP_2668 | ribK | MCP_2668 | MCP_2669 | Putative Na(+)/H(+) antiporter. | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.532 |
dfp | MCP_1651 | MCP_2675 | MCP_1651 | Bifunctional protein. | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | 0.406 |
dfp | ribB | MCP_2675 | MCP_2670 | Bifunctional protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.546 |
glyA | guaB | MCP_0294 | MCP_2987 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.679 |
glyA | ribB | MCP_0294 | MCP_2670 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.533 |
glyA | rps2p | MCP_0294 | MCP_1641 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.458 |
guaB | glyA | MCP_2987 | MCP_0294 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.679 |
guaB | ribB | MCP_2987 | MCP_2670 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.587 |
guaB | ribH | MCP_2987 | MCP_1453 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.755 |
guaB | rps2p | MCP_2987 | MCP_1641 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.687 |
ribB | MCP_1048 | MCP_2670 | MCP_1048 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine reductase. | 0.882 |
ribB | MCP_1651 | MCP_2670 | MCP_1651 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Putative 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine reductase. | 0.880 |