STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2686Putative hydrogenase maturation protease. (161 aa)    
Predicted Functional Partners:
MCP_2685
Putative NADH:ubiquinone dehydrogenase.
 
   
 0.836
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
   0.595
MCP_2640
Putative [NiFe]-hydrogenase large subunit.
 
  
 0.589
hypA
Probable hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.540
frhA-1
Coenzyme F420 hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.531
MCP_2638
4Fe-4S ferredoxin, iron-sulfur binding protein.
 
  
 0.498
frhA-2
Coenzyme F420 hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.490
hypC
Hydrogenase expression/formation protein HypC.
 
  
 0.481
hypF
Carbamoyltransferase HypF.
 
   
 0.459
frhG-2
Coenzyme F420 hydrogenase subunit gamma.
 
  
 0.434
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.