STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
MCP_2686Putative hydrogenase maturation protease. (161 aa)    
Predicted Functional Partners:
MCP_2685
Putative NADH:ubiquinone dehydrogenase.
 
   
 0.824
hypA
Probable hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.726
hypF
Carbamoyltransferase HypF.
 
   
 0.571
MCP_2640
Putative [NiFe]-hydrogenase large subunit.
 
  
 0.537
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
   0.504
MCP_2638
4Fe-4S ferredoxin, iron-sulfur binding protein.
 
  
 0.477
frhA-1
Coenzyme F420 hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.476
hypC
Hydrogenase expression/formation protein HypC.
 
  
 0.466
frhG-2
Coenzyme F420 hydrogenase subunit gamma.
 
  
 0.444
frhA-2
Coenzyme F420 hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.431
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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