STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (352 aa)    
Predicted Functional Partners:
fcl
Putative GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.999
MCP_0103
Mannose-1-phosphate guanyltransferase.
    
 0.914
MCP_0273
Putative nucleotidyl transferase.
  
  
 0.810
MCP_0949
Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).
  
  
 0.800
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
    
   0.693
MCP_0244
Hypothetical protein; Contains one Methyltransferase type 11 domain (IPR013216); Contains two Glycosyl transferase, family 2 domains (IPR001173).
  
  
 0.677
rfbB
dTDP-glucose 4,6-dehydratase.
     
0.614
rfbC
Putative dTDP-4-dehydrorhamnose 3,5-epimerase.
     
 0.585
MCP_0773
Putative nucleotide sugar epimerase/dehydratase.
  
 
 0.477
MCP_0863
Putative nucleotide sugar epimerase/dehydratase.
  
 
 0.477
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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