Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_2749Conserved hypothetical protein; Belongs to the Protein of unknown function DUF35 family (IPR002878). (129 aa)    
Predicted Functional Partners:
MCP_2747
Putative hydroxymethylglutaryl-coenzyme A synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 
 0.999
MCP_2748
acyl-CoA C-acyltransferases.
 
 
 0.999
MCP_2746
Putative HTH-type transcriptional regulator.
 
    0.957
cyaB
Adenylate cyclase.
       0.582
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
       0.555
MCP_1837
Conserved hypothetical protein.
       0.537
MCP_0646
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF124 family (IPR002838).
       0.533
MCP_1556
snoRNA binding protein Nop56 homolog.
       0.529
flpA
rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.529
MCP_2745
Hypothetical protein.
       0.523
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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