Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_2760Conserved hypothetical protein; Belongs to the Protein of unknown function DUF169 family (IPR003748). (223 aa)    
Predicted Functional Partners:
MCP_0857
Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
 
     0.607
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
       0.578
trxA
Thioredoxin.
  
  
 0.514
mtrH
Tetrahydromethanopterin S-methyltransferase subunit H.
  
     0.462
MCP_0266
Conserved hypothetical protein.
 
     0.451
MCP_2758
Conserved hypothetical protein.
       0.446
MCP_1063
Putative CoA enzyme activase.
 
     0.428
atw-2
Putative methylcoenzyme M reductase system component A2.
 
     0.415
fwdF-1
Tungsten-containing formylmethanofuran dehydrogenase subunit F.
 
     0.412
atw-1
Putative methylcoenzyme M reductase system component A2.
 
     0.409
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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