Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mvhA-2F420-non-reducing hydrogenase subunit A. (470 aa)    
Predicted Functional Partners:
mvhG-2
F420-non-reducing hydrogenase subunit G.
 
 
 0.995
mvhG-1
F420-non-reducing hydrogenase subunit G.
 
 
 0.964
frhG-1
Coenzyme F420 hydrogenase subunit gamma.
 
 
 0.949
frhG-2
Coenzyme F420 hydrogenase subunit gamma.
 
 
 0.936
mvhD-2
F420-non-reducing hydrogenase iron-sulfur subunit D.
 
 
 0.892
mvhD-1
F420-non-reducing hydrogenase iron-sulfur subunit D.
 
 
 0.891
hypA
Probable hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.877
hdrA-1
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.849
hdrA-2
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.849
vhtG
F420-non-reducing hydrogenase small subunit.
  
 
 0.844
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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