STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2786Conserved hypothetical protein; Belongs to the Protein of unknown function DUF509 family (IPR007510). (170 aa)    
Predicted Functional Partners:
gcp
Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
    
 
 0.922
MCP_2151
Conserved hypothetical protein; Belongs to the RIO kinase family (IPR000687); Contains one Protein kinasedomain (IPR000719).
    
 
 0.922
hjm
Holliday junction migration helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
       0.711
MCP_2246
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF106, transmembrane family (IPR002809).
 
     0.672
MCP_0724
Putative DNA-directed RNA polymerase subunit F.
  
     0.659
MCP_2990
Single-stranded DNA-binding replication protein.
  
     0.644
MCP_2814
Putative ArsR family transcriptional regulator.
  
     0.634
MCP_0003
Conserved hypothetical protein.
  
     0.631
MCP_1513
Conserved hypothetical protein.
  
     0.628
MCP_2297
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF1621 family (IPR012426).
  
     0.617
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.