STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2870Putative HTH-type transcriptional regulator. (320 aa)    
Predicted Functional Partners:
tiaS
Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.842
MCP_2869
Conserved hypothetical protein.
 
     0.731
MCP_2831
Conserved hypothetical protein; Contains one Adenylate/cytidine kinase, N-terminal domain (IPR011769); Belongs to the Protein of unknown function DUF54 family (IPR002739).
 
     0.705
MCP_1516
Archaeosine tRNA-ribosyltransferase.
  
     0.673
MCP_0292
Conserved hypothetical protein.
 
     0.672
MCP_1648
Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0179 family (IPR005369).
  
     0.670
MCP_1751
Conserved hypothetical protein; Similar to JAMM-like protein in Archaeoglobus fulgidus (O28085, AF_2198).
  
     0.655
MCP_2850
Conserved hypothetical protein.
 
     0.655
priA
Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...]
  
     0.647
MCP_2849
Putative single-stranded DNA-binding replication protein.
 
     0.639
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.