STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2880Conserved hypothetical protein; Belongs to the HI0933-like family (IPR004792). (416 aa)    
Predicted Functional Partners:
MCP_2879
Ferredoxin.
       0.775
MCP_2881
Conserved hypothetical protein.
       0.773
purT-2
Phosphoribosylglycinamide formyltransferase 2.
 
     0.701
MCP_1516
Archaeosine tRNA-ribosyltransferase.
 
     0.594
engB
GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation.
 
     0.577
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
       0.529
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.516
MCP_0090
Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0004 family (IPR005839); Contains one Cobalamin vitamin B12-binding domain (IPR006158).; Contains one Elongator protein 3/MiaB/NifB domain (IPR006638).; Contains one Radical SAM domain (IPR007197).
 
  
 0.477
MCP_1168
Putative geranylgeranyl reductase.
 
  
 0.471
cofC
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
       0.461
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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