STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_2898Putative transcriptional regulator; Contains an extra Cystathionine-beta-synthase domain (IPR000644) in the C-terminal region. (291 aa)    
Predicted Functional Partners:
MCP_2304
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
  
    0.764
MCP_0296
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
  
    0.621
MCP_0295
Conserved hypothetical protein; Contains at least two CBS domains (IPR000644).
  
    0.549
MCP_0297
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
  
    0.529
MCP_0137
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF460 family (IPR007408).
  
     0.526
tfe
Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...]
  
     0.461
MCP_0298
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
  
    0.460
MCP_1981
Conserved hypothetical protein; Contains at least one Cystathionine-beta-synthasedomain (IPR000644); Contains one ParB-like nuclease domain (IPR003115).
  
     0.430
MCP_2872
Conserved hypothetical protein; Contains two CBS domains (IPR000644).
  
    0.429
MCP_2897
Conserved hypothetical protein; Contains one Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core domain (IPR011576).
       0.428
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.