STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiZPutative adenosylcobinamide amidohydrolase. (302 aa)    
Predicted Functional Partners:
cobD
Probable cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.991
cobB
Probable cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
   
 0.825
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.825
MCP_1958
Conserved hypothetical protein; Contains one Protein of unknown function DUF102 domain (IPR002805); Belongs to the UPF0284 family.
 
   
 0.797
MCP_2917
Putative iron compound ABC transporter iron compound binding protein.
 
  
 0.774
MCP_2427
Putative glycerophosphoryl diester phosphodiesterase.
      0.615
MCP_1952
L-threonine-O-3-phosphate decarboxylase.
 
   
 0.573
MCP_2915
TetR family transcriptional regulator.
       0.555
MCP_2432
Conserved hypothetical protein.
 
     0.549
MCP_2914
Conserved hypothetical protein; Contains two Sterol-sensing 5TM box domains (IPR000731); Contains one Calcium-binding EF-hand domain (IPR004869).; Contains one MMPL domain (IPR004869).
       0.540
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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