STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemDuroporphyrinogen-III synthase. (261 aa)    
Predicted Functional Partners:
cobA
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.999
hemC
Probable porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 0.999
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.984
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.938
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
 
  
 0.910
cysG
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Bifunctional protein.
 
  
 0.837
MCP_0632
Conserved hypothetical protein; Contains one Amino acid-binding ACT domain (IPR002912).
  
    0.730
trkA-1
Trk system potassium uptake protein TrkA homolog.
  
    0.667
trkA-2
Trk system potassium uptake protein TrkA homolog.
  
    0.667
MCP_2922
Hypothetical protein; Contains at least one PBS lyase HEAT-like repeat (IPR004155).
 
   
 0.655
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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