STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCFamily D DNA polymerase large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1129 aa)    
Predicted Functional Partners:
polB
Family D DNA polymerase small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
 
 
 0.980
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 
 
 0.956
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.665
MCP_1743
Putative single-stranded-DNA-specific exonuclease RecJ.
 
     0.663
MCP_0725
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF655 family (IPR007003).
  
     0.656
rps27ae
30S ribosomal protein S27ae; Belongs to the eukaryotic ribosomal protein eS31 family.
  
     0.654
MCP_1533
Belongs to the Conserved hypothetical protein 62 family (IPR004426).
  
     0.640
recJ
Single-stranded DNA-specific exonuclease RecJ.
 
     0.621
spt5
Putative ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.621
MCP_0829
Conserved hypothetical protein.
 
     0.605
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.