Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mobAProbable molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (201 aa)    
Predicted Functional Partners:
moeA-1
Putative molybdopterin biosynthesis protein.
 
 0.995
moeA-2
Putative molybdopterin biosynthesis protein.
 
 0.978
moaA
Probable molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.780
MCP_2938
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF92, transmembrane family (IPR002794).
       0.767
fdhD
Protein FdhD homolog; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 
 0.751
MCP_2421
Molybdopterin-guanine dinucleotide biosynthesis MobB/molybdopterin biosynthesis MoaE; Bifunctional protein.
 
  
 0.626
fdhA-2
Formate dehydrogenase alpha chain.
 
   
 0.613
fdhA-1
Formate dehydrogenase alpha chain.
 
   
 0.607
MCP_2939
Di-trans-poly-cis-decaprenylcistransferase family protein.
     
 0.606
MCP_1258
Pyruvate synthase beta chain; Similar to Ketoisovalerate oxidoreductase beta VorB in Pyrococcus furiosus (Q51802).
  
  
 0.547
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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