Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_2940Belongs to the Conserved hypothetical protein 374 family (IPR005242). (343 aa)    
Predicted Functional Partners:
MCP_2939
Di-trans-poly-cis-decaprenylcistransferase family protein.
     
 0.740
MCP_0244
Hypothetical protein; Contains one Methyltransferase type 11 domain (IPR013216); Contains two Glycosyl transferase, family 2 domains (IPR001173).
 
  
 0.704
MCP_0949
Hypothetical protein; Contains one UDP-glucose/GDP-mannose dehydrogenase domain (IPR001732); Contains one Glycosyl transferase, family 2 domain (IPR001173).
     
 0.646
MCP_2914
Conserved hypothetical protein; Contains two Sterol-sensing 5TM box domains (IPR000731); Contains one Calcium-binding EF-hand domain (IPR004869).; Contains one MMPL domain (IPR004869).
     
 0.596
MCP_2438
Asparagine synthase.
     
 0.593
MCP_2938
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF92, transmembrane family (IPR002794).
 
     0.585
MCP_2941
Conserved hypothetical protein; Contains one Protein of unknown function DUF151 domain (IPR003729).
       0.546
ppnK
Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.536
thiL
Putative thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.535
MCP_0624
Conserved hypothetical protein; Contains one Radical SAM domain (IPR007197).
       0.529
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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