Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mfnBConserved hypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (231 aa)    
Predicted Functional Partners:
MCP_1841
Putative aspartate aminotransferase.
    
 0.900
MCP_2811
Conserved hypothetical protein; Contains one Histidine biosynthesis domain (IPR006062); Belongs to the HisA/HisF family.
 
   
 0.867
MCP_0670
Putative amino acid kinase.
 
   
 0.790
MCP_1325
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF66 family (IPR002756); Belongs to the Hydantoinase/oxoprolinase family (IPR002821).
 
   
 0.781
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.758
MCP_1324
Conserved hypothetical protein; Contains one ATP-grasp fold, DUF201-type domain (IPR003806).
 
   
 0.756
fwdA-1
Tungsten-containing formylmethanofuran dehydrogenase subunit A.
 
   
 0.755
fwdA-2
Tungsten-containing formylmethanofuran dehydrogenase subunit A.
 
   
 0.755
MCP_0453
Belongs to the Dihydropteroate synthase-related protein synthase-related protein family (IPR005236).
 
   
 0.744
MCP_1182
Conserved hypothetical protein; Belongs to the ShortTriphosphoribosyl-dephospho-CoA protein family (IPR002736).
 
   
 0.737
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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