STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITCHItchy E3 ubiquitin protein ligase. (843 aa)    
Predicted Functional Partners:
RPS27A
Ribosomal protein S27a.
    
 0.970
CFLAR
CASP8 and FADD like apoptosis regulator.
    
 0.960
UBE2L3
Ubiquitin conjugating enzyme E2 L3.
    
 0.945
TRAF6
TNF receptor associated factor 6.
    
 0.942
NUMB
NUMB endocytic adaptor protein.
    
 0.942
TXNIP
Thioredoxin interacting protein.
    
 
 0.940
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
  
 
0.940
ENSNPEP00000020308
annotation not available
 
  
 
0.914
MDM2
MDM2 proto-oncogene.
    
 0.892
CBL
Cbl proto-oncogene.
    
 0.891
Your Current Organism:
Nothoprocta perdicaria
NCBI taxonomy Id: 30464
Other names: N. perdicaria
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.