STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY4Sprouty RTK signaling antagonist 4. (304 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.865
CBLB
Cbl proto-oncogene B.
    
 0.865
GRB2
Growth factor receptor bound protein 2.
    
 0.731
GRAP2
GRB2 related adaptor protein 2.
    
 0.721
GRAP
GRB2 related adaptor protein.
    
 0.721
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.710
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.700
PPP2CA
Protein phosphatase 2 catalytic subunit alpha.
    
  0.679
PPP2CB
Protein phosphatase 2 catalytic subunit beta.
    
  0.679
SPRY1
Sprouty RTK signaling antagonist 1.
   
0.667
Your Current Organism:
Nothoprocta perdicaria
NCBI taxonomy Id: 30464
Other names: N. perdicaria
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.