STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD2SMAD family member 2. (467 aa)    
Predicted Functional Partners:
SMAD4
SMAD family member 4.
   
0.998
SMURF2
SMAD specific E3 ubiquitin protein ligase 2.
    
 0.990
TGFBR1
Transforming growth factor beta receptor 1.
   
 0.990
SMAD3
SMAD family member 3.
  
  
0.989
ZFYVE9
Zinc finger FYVE-type containing 9.
   
 0.988
TGFBR2
Transforming growth factor beta receptor 2.
   
 0.984
FOXO1
Forkhead box O1.
    
 0.973
BMPR1A
Bone morphogenetic protein receptor type 1A.
   
 0.973
BMPR1B
Bone morphogenetic protein receptor type 1B.
   
 0.972
ZFYVE16
Zinc finger FYVE-type containing 16.
   
 0.972
Your Current Organism:
Bos grunniens
NCBI taxonomy Id: 30521
Other names: B. grunniens, Bos mutus grunniens, Peophagus grunniens, domestic yak, yak
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.