STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK1Serine/threonine-protein kinase PLK. (602 aa)    
Predicted Functional Partners:
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 0.997
CDC20
Cell division cycle 20.
   
 0.995
CDC20B
Cell division cycle 20B.
   
 0.994
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.993
CCNB2
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.993
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.992
FBXO43
F-box protein 43.
   
 0.990
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
0.988
CDC25A
Cell division cycle 25A.
   
 0.985
BUB1B
Uncharacterized protein.
   
 0.985
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.