STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (305 aa)    
Predicted Functional Partners:
AVPR1B
Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
   
  
 0.934
CIDEA
Cell death inducing DFFA like effector a.
   
  
 0.764
ADRB3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.744
PPARGC1A
PPARG coactivator 1 alpha.
   
  
 0.725
PRDM16
PR/SET domain 16.
      
 0.723
TMEM26
Transmembrane protein 26.
   
  
 0.703
ADIPOQ
Adiponectin, C1Q and collagen domain containing.
   
  
 0.695
LIPE
Lipase E, hormone sensitive type.
   
  
 0.669
ELOVL3
Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...]
      
 0.660
PLIN1
Perilipin; Belongs to the perilipin family.
    
 
 0.640
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.