STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL6STInterleukin 6 signal transducer. (935 aa)    
Predicted Functional Partners:
IL6
Interleukin 6.
    
 0.988
IL6R
Interleukin 6 receptor.
   
0.987
LIF
LIF interleukin 6 family cytokine.
    
 0.981
IL27
Interleukin 27.
    
 0.961
JAK1
Tyrosine-protein kinase.
    
 0.954
OSM
Oncostatin M.
    
 0.934
JAK2
Tyrosine-protein kinase.
    
 0.902
LIFR
LIF receptor subunit alpha.
    
0.893
JAK3
Tyrosine-protein kinase.
    
 0.884
STAT3
Signal transducer and activator of transcription.
    
 0.876
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.