STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITM2CIntegral membrane protein 2C. (288 aa)    
Predicted Functional Partners:
KIAA1755
KIAA1755.
      
 0.723
EML6
EMAP like 6.
      
 0.723
PDZD11
PDZ domain containing 11.
   
  
 0.695
SLC35A5
Solute carrier family 35 member A5.
   
  
 0.678
SYT11
Synaptotagmin 11.
    
 
 0.587
EPB41L4A
Erythrocyte membrane protein band 4.1 like 4A.
      
 0.581
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.574
MAN1A1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.499
ARHGAP1
Rho GTPase activating protein 1.
      
 0.497
STXBP5
Syntaxin binding protein 5.
      
 0.497
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.