STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO11SPO11 initiator of meiotic double stranded breaks. (395 aa)    
Predicted Functional Partners:
MSH4
MutS homolog 4.
   
 
 0.858
HORMAD1
HORMA domain containing 1.
   
  
 0.847
SYCP3
Synaptonemal complex protein 3.
      
 0.839
MUS81
MUS81 structure-specific endonuclease subunit.
    
 
 0.834
REC8
REC8 meiotic recombination protein.
    
 
 0.826
REC114
REC114 meiotic recombination protein.
   
  
 0.820
DMC1
DNA meiotic recombinase 1; Belongs to the RecA family.
    
 0.792
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
   
 
 0.760
STRA8
Uncharacterized protein.
      
 0.745
SYCE1
Synaptonemal complex central element protein 1.
      
 0.742
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.