node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A4W2CYN0 | A0A4W2E2S2 | A0A4W2CYN0 | A0A4W2E2S2 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | S-adenosylmethionine decarboxylase proenzyme. | 0.954 |
A0A4W2CYN0 | BHMT | A0A4W2CYN0 | A0A4W2DQI3 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | Betaine--homocysteine S-methyltransferase. | 0.969 |
A0A4W2CYN0 | BHMT2 | A0A4W2CYN0 | A0A4W2DAM6 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | 0.923 |
A0A4W2CYN0 | DNMT1 | A0A4W2CYN0 | A0A4W2IBK7 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.921 |
A0A4W2CYN0 | DNMT3A | A0A4W2CYN0 | A0A4W2DG25 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.959 |
A0A4W2CYN0 | DNMT3B | A0A4W2CYN0 | A0A4W2H0Q4 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.893 |
A0A4W2CYN0 | MAT1A | A0A4W2CYN0 | A0A4W2DNI5 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.995 |
A0A4W2CYN0 | MAT2A | A0A4W2CYN0 | A0A4W2EB67 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.988 |
A0A4W2CYN0 | MTR | A0A4W2CYN0 | A0A4W2CH68 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |
A0A4W2CYN0 | TAT | A0A4W2CYN0 | A0A4W2CFP5 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.948 |
A0A4W2E2S2 | A0A4W2CYN0 | A0A4W2E2S2 | A0A4W2CYN0 | S-adenosylmethionine decarboxylase proenzyme. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.954 |
A0A4W2E2S2 | DNMT1 | A0A4W2E2S2 | A0A4W2IBK7 | S-adenosylmethionine decarboxylase proenzyme. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.819 |
A0A4W2E2S2 | MAT1A | A0A4W2E2S2 | A0A4W2DNI5 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.963 |
A0A4W2E2S2 | MAT2A | A0A4W2E2S2 | A0A4W2EB67 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.878 |
A0A4W2E2S2 | TAT | A0A4W2E2S2 | A0A4W2CFP5 | S-adenosylmethionine decarboxylase proenzyme. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.407 |
BHMT | A0A4W2CYN0 | A0A4W2DQI3 | A0A4W2CYN0 | Betaine--homocysteine S-methyltransferase. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.969 |
BHMT | BHMT2 | A0A4W2DQI3 | A0A4W2DAM6 | Betaine--homocysteine S-methyltransferase. | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | 0.892 |
BHMT | MAT1A | A0A4W2DQI3 | A0A4W2DNI5 | Betaine--homocysteine S-methyltransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.987 |
BHMT | MAT2A | A0A4W2DQI3 | A0A4W2EB67 | Betaine--homocysteine S-methyltransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.945 |
BHMT | MTR | A0A4W2DQI3 | A0A4W2CH68 | Betaine--homocysteine S-methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.963 |