STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESPL1Extra spindle pole bodies like 1, separase. (2100 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.993
SMC3
Structural maintenance of chromosomes protein.
   
 0.992
PTTG1
Uncharacterized protein.
   
 0.989
LOC113899187
Uncharacterized protein.
   
 0.988
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.985
RAD21
RAD21 cohesin complex component.
   
 0.984
SMC1A
Structural maintenance of chromosomes protein.
   
 0.973
LOC113896623
Uncharacterized protein.
   
 0.969
A0A4W2DCT4
Uncharacterized protein.
   
 0.969
CDC20
Cell division cycle 20.
   
 0.967
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.