node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRCA2 | FANCA | A0A4W2BPN3 | A0A4W2C9V8 | BRCA2 DNA repair associated. | FA complementation group A. | 0.599 |
BRCA2 | FANCC | A0A4W2BPN3 | A0A4W2HU13 | BRCA2 DNA repair associated. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.487 |
BRCA2 | FANCD2 | A0A4W2BPN3 | A0A4W2DTJ3 | BRCA2 DNA repair associated. | FA complementation group D2. | 0.998 |
BRCA2 | FANCG | A0A4W2BPN3 | A0A4W2CTU4 | BRCA2 DNA repair associated. | FA complementation group G. | 0.761 |
BRCA2 | FANCI | A0A4W2BPN3 | A0A4W2C6X2 | BRCA2 DNA repair associated. | FA complementation group I. | 0.643 |
BRCA2 | FANCL | A0A4W2BPN3 | A0A4W2CI12 | BRCA2 DNA repair associated. | FA complementation group L. | 0.489 |
BRCA2 | FANCM | A0A4W2BPN3 | A0A4W2CC43 | BRCA2 DNA repair associated. | FA complementation group M. | 0.682 |
BRCA2 | UBE2T | A0A4W2BPN3 | A0A4W2C223 | BRCA2 DNA repair associated. | Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. | 0.441 |
FAAP100 | FAN1 | A0A4W2CAZ1 | A0A4W2EGH8 | FA core complex associated protein 100. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.529 |
FAAP100 | FANCA | A0A4W2CAZ1 | A0A4W2C9V8 | FA core complex associated protein 100. | FA complementation group A. | 0.999 |
FAAP100 | FANCC | A0A4W2CAZ1 | A0A4W2HU13 | FA core complex associated protein 100. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.999 |
FAAP100 | FANCD2 | A0A4W2CAZ1 | A0A4W2DTJ3 | FA core complex associated protein 100. | FA complementation group D2. | 0.995 |
FAAP100 | FANCG | A0A4W2CAZ1 | A0A4W2CTU4 | FA core complex associated protein 100. | FA complementation group G. | 0.999 |
FAAP100 | FANCI | A0A4W2CAZ1 | A0A4W2C6X2 | FA core complex associated protein 100. | FA complementation group I. | 0.991 |
FAAP100 | FANCL | A0A4W2CAZ1 | A0A4W2CI12 | FA core complex associated protein 100. | FA complementation group L. | 0.999 |
FAAP100 | FANCM | A0A4W2CAZ1 | A0A4W2CC43 | FA core complex associated protein 100. | FA complementation group M. | 0.999 |
FAAP100 | UBE2T | A0A4W2CAZ1 | A0A4W2C223 | FA core complex associated protein 100. | Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. | 0.992 |
FAN1 | FAAP100 | A0A4W2EGH8 | A0A4W2CAZ1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA core complex associated protein 100. | 0.529 |
FAN1 | FANCA | A0A4W2EGH8 | A0A4W2C9V8 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group A. | 0.609 |
FAN1 | FANCC | A0A4W2EGH8 | A0A4W2HU13 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.495 |