STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4W2EB55Uncharacterized protein. (345 aa)    
Predicted Functional Partners:
AP2A2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.934
A0A4W2BXG6
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.882
AP2M1
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.882
AP2B1
Uncharacterized protein.
    
  0.860
VAMP4
Vesicle associated membrane protein 4.
   
 0.840
A0A4W2E3N8
B2-adapt-app_C domain-containing protein.
    
  0.836
AP1B1
AP complex subunit beta.
    
  0.809
AP2S1
Adaptor related protein complex 2 subunit sigma 1.
    
  0.715
GCC1
GRIP and coiled-coil domain containing 1.
   
 
 0.649
DAGLB
Diacylglycerol lipase beta.
      
 0.605
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.