STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNOCyclin O; Belongs to the cyclin family. (425 aa)    
Predicted Functional Partners:
CDC20B
Cell division cycle 20B.
   
 0.782
CDC20
Cell division cycle 20.
   
 0.721
MCIDAS
Multiciliate differentiation and DNA synthesis associated cell cycle protein.
   
  
 0.714
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.662
PLK4
Polo like kinase 4.
   
 0.653
INTU
Inturned planar cell polarity protein.
   
 0.649
CKS2
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.620
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
0.591
CCNE2
Cyclin E2; Belongs to the cyclin family.
   
0.591
DEUP1
Deuterosome assembly protein 1.
    
 
 0.582
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.