STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC2NPC intracellular cholesterol transporter 2. (149 aa)    
Predicted Functional Partners:
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.998
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.922
SCAP
SREBF chaperone.
   
 0.815
APOB
Apolipoprotein B.
     
 0.616
GM2A
GM2 ganglioside activator.
   
  
 0.560
CD52
CD52 molecule.
      
 0.555
A0A4W2EBF7
Uncharacterized protein.
     
 0.540
LAMP1
Lysosomal associated membrane protein 1.
   
  
 0.503
ATP7B
ATPase copper transporting beta.
      
 0.495
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
  
 0.430
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.