node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCKDHB | DHTKD1 | A0A4W2E1C9 | A0A4W2E2Q2 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dehydrogenase E1 and transketolase domain containing 1. | 0.731 |
BCKDHB | DLD | A0A4W2E1C9 | A0A4W2H686 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dihydrolipoyl dehydrogenase. | 0.990 |
BCKDHB | DLST | A0A4W2E1C9 | A0A4W2GWM3 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dihydrolipoamide S-succinyltransferase. | 0.979 |
BCKDHB | OGDH | A0A4W2E1C9 | A0A4W2CTJ3 | Branched chain keto acid dehydrogenase E1 subunit beta. | Oxoglutarate dehydrogenase. | 0.677 |
BCKDHB | OGDHL | A0A4W2E1C9 | A0A4W2D5E1 | Branched chain keto acid dehydrogenase E1 subunit beta. | Oxoglutarate dehydrogenase like. | 0.677 |
BCKDHB | PDHB | A0A4W2E1C9 | A0A4W2BKV6 | Branched chain keto acid dehydrogenase E1 subunit beta. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.633 |
BCKDHB | SUCLA2 | A0A4W2E1C9 | A0A4W2DMF6 | Branched chain keto acid dehydrogenase E1 subunit beta. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.424 |
BCKDHB | SUCLG1 | A0A4W2E1C9 | A0A4W2CBS2 | Branched chain keto acid dehydrogenase E1 subunit beta. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.714 |
BCKDHB | SUCLG2 | A0A4W2E1C9 | A0A4W2BM33 | Branched chain keto acid dehydrogenase E1 subunit beta. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.615 |
BCKDHB | TMEM91 | A0A4W2E1C9 | A0A4W2E4T4 | Branched chain keto acid dehydrogenase E1 subunit beta. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
DHTKD1 | BCKDHB | A0A4W2E2Q2 | A0A4W2E1C9 | Dehydrogenase E1 and transketolase domain containing 1. | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.731 |
DHTKD1 | DLD | A0A4W2E2Q2 | A0A4W2H686 | Dehydrogenase E1 and transketolase domain containing 1. | Dihydrolipoyl dehydrogenase. | 0.984 |
DHTKD1 | DLST | A0A4W2E2Q2 | A0A4W2GWM3 | Dehydrogenase E1 and transketolase domain containing 1. | Dihydrolipoamide S-succinyltransferase. | 0.996 |
DHTKD1 | OGDH | A0A4W2E2Q2 | A0A4W2CTJ3 | Dehydrogenase E1 and transketolase domain containing 1. | Oxoglutarate dehydrogenase. | 0.556 |
DHTKD1 | OGDHL | A0A4W2E2Q2 | A0A4W2D5E1 | Dehydrogenase E1 and transketolase domain containing 1. | Oxoglutarate dehydrogenase like. | 0.551 |
DHTKD1 | PDHB | A0A4W2E2Q2 | A0A4W2BKV6 | Dehydrogenase E1 and transketolase domain containing 1. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.719 |
DHTKD1 | SUCLA2 | A0A4W2E2Q2 | A0A4W2DMF6 | Dehydrogenase E1 and transketolase domain containing 1. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.910 |
DHTKD1 | SUCLG1 | A0A4W2E2Q2 | A0A4W2CBS2 | Dehydrogenase E1 and transketolase domain containing 1. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.957 |
DHTKD1 | SUCLG2 | A0A4W2E2Q2 | A0A4W2BM33 | Dehydrogenase E1 and transketolase domain containing 1. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.908 |
DHTKD1 | TMEM91 | A0A4W2E2Q2 | A0A4W2E4T4 | Dehydrogenase E1 and transketolase domain containing 1. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.687 |