Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF170Ring finger protein 170. (260 aa)    
Predicted Functional Partners:
ERLIN2
ER lipid raft associated 2.
    
 
 0.990
ERLIN1
ER lipid raft associated 1.
    
 
 0.989
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 
 0.869
CGRRF1
Cell growth regulator with ring finger domain 1.
      
 0.805
TMUB2
Transmembrane and ubiquitin like domain containing 2.
    
 
 0.770
UBE2J1
Ubiquitin conjugating enzyme E2 J1.
    
 
 0.749
ENSVPAP00000001912
annotation not available
      
 0.722
ENSVPAP00000008719
annotation not available
      
 0.683
HERPUD2
HERPUD family member 2.
      
 0.683
ENSVPAP00000003360
annotation not available
      
 0.672
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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