Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MITFMelanocyte inducing transcription factor. (499 aa)    
Predicted Functional Partners:
MAPK7
Mitogen-activated protein kinase 7.
    
 0.984
KIT
KIT proto-oncogene, receptor tyrosine kinase.
   
 0.983
KITLG
KIT ligand.
     
 0.974
LEF1
Lymphoid enhancer binding factor 1.
    
 0.967
SUMO1
Small ubiquitin like modifier 1.
    
 0.965
TYR
Tyrosinase.
   
 0.964
SIRT1
Sirtuin 1.
     
 0.960
XPO1
Exportin 1.
     
 0.959
TNFSF11
TNF superfamily member 11.
     
 0.950
CREBBP
CREB binding protein.
    
 0.942
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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