Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM227AFamily with sequence similarity 227 member A. (640 aa)    
Predicted Functional Partners:
SMPDL3A
Sphingomyelin phosphodiesterase acid like 3A.
      
 0.675
MTFR2
Mitochondrial fission regulator 2.
      
 0.615
RBBP9
RB binding protein 9, serine hydrolase.
      
 0.615
CMBL
Carboxymethylenebutenolidase homolog.
      
 0.523
CCDC62
Coiled-coil domain containing 62.
      
 0.523
RND2
Rho family GTPase 2.
      
 0.521
IRF4
Interferon regulatory factor 4.
      
 0.519
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C.
      
 0.500
BBS10
Bardet-Biedl syndrome 10.
      
 0.442
FBXL4
F-box and leucine rich repeat protein 4.
      
 0.435
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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