Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSDMAGasdermin A. (446 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4.
  
 
 
 0.719
GSDME
Gasdermin E.
      
 0.609
ENSVPAP00000000819
annotation not available
    
 
 0.584
GART
annotation not available
      
 0.551
NLRC4
NLR family CARD domain containing 4.
      
 0.522
ENSVPAP00000009484
annotation not available
      
 0.522
NAIP
NLR family apoptosis inhibitory protein.
      
 0.516
ENSVPAP00000006558
annotation not available
      
 0.516
MLKL
Mixed lineage kinase domain like pseudokinase.
    
 
 0.515
CASP3
Caspase 3.
   
  
 0.500
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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