Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF145Ring finger protein 145. (555 aa)    
Predicted Functional Partners:
ERLEC1
Endoplasmic reticulum lectin 1.
   
 0.865
COPS5
COP9 signalosome subunit 5.
    
 
 0.858
DERL2
Derlin 2.
    
 0.848
MARCHF6
Membrane associated ring-CH-type finger 6.
    
 
 0.838
DERL1
Derlin 1.
    
 0.828
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase.
   
 
 0.813
RNF185
Ring finger protein 185.
    
 
 0.753
UBXN1
UBX domain protein 1.
    
 0.729
SPATA5L1
Spermatogenesis associated 5 like 1.
    
 0.723
VCP
Valosin containing protein.
    
 0.723
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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