Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SORCS3Sortilin related VPS10 domain containing receptor 3. (1204 aa)    
Predicted Functional Partners:
SORT1
Sortilin 1.
    
 
 0.917
VPS35
VPS35 retromer complex component.
    
 
 0.780
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.759
VPS26A
VPS26, retromer complex component A.
    
 
 0.734
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
      
 0.733
CLTC
Clathrin heavy chain.
    
 0.706
APP
Amyloid beta precursor protein.
    
 0.692
CDH8
Cadherin 8.
   
 
 0.667
SLC39A12
Solute carrier family 39 member 12.
   
  
 0.642
CCDC175
Coiled-coil domain containing 175.
      
 0.615
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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