Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAD17RAD17 checkpoint clamp loader component. (591 aa)    
Predicted Functional Partners:
RFC4
Replication factor C subunit 4.
    
 0.999
RFC3
Replication factor C subunit 3.
   
 0.999
ENSVPAP00000009840
annotation not available
    
 0.999
ATR
ATR serine/threonine kinase.
    
 0.996
RAD1
RAD1 checkpoint DNA exonuclease.
   
 0.996
RAD9B
RAD9 checkpoint clamp component B.
   
 0.993
WRN
WRN RecQ like helicase.
  
 0.988
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.984
BLM
BLM RecQ like helicase.
  
 0.980
ATM
ATM serine/threonine kinase.
    
 0.980
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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