Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAD18RAD18 E3 ubiquitin protein ligase. (458 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen.
   
 0.998
UBE2A
Ubiquitin conjugating enzyme E2 A.
    
 0.995
HLTF
Helicase like transcription factor.
   
 0.992
SLF1
SMC5-SMC6 complex localization factor 1.
   
 
 0.989
POLH
DNA polymerase eta.
    
 
 0.988
SHPRH
SNF2 histone linker PHD RING helicase.
    
 0.987
FANCM
FA complementation group M.
   
 
 0.979
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
    
 0.978
UBE2B
Ubiquitin conjugating enzyme E2 B.
    
 0.971
ENSVPAP00000002735
annotation not available
    
 0.971
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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